A hypotonic-hyporesponsive episode (HHE) is defined as sudden onset of poor muscle tone, , and pale or bluish skin occurring within 48 hours after vaccination, most commonly pertussis vaccination. An HHE is estimated to occur after 1 in 4,762 to 1 in 1,408 doses of whole cell pertussis vaccine, and after 1 in 14,286 to 1 in 2,778 doses of acellular pertussis vaccine.
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| - Hypotonic-hyporesponsive episode (en)
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| - A hypotonic-hyporesponsive episode (HHE) is defined as sudden onset of poor muscle tone, , and pale or bluish skin occurring within 48 hours after vaccination, most commonly pertussis vaccination. An HHE is estimated to occur after 1 in 4,762 to 1 in 1,408 doses of whole cell pertussis vaccine, and after 1 in 14,286 to 1 in 2,778 doses of acellular pertussis vaccine. (en)
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| - Hypotonic-hyporesponsive episode (HHE) (en)
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name
| - Hypotonic-hyporesponsive episode (en)
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onset
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symptoms
| - Hypotonia, hyporesponsiveness, pallor, cyanosis. (en)
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treatment
| - Usually resolves on its own, management involves checking the airway, breathing, and circulation, and hospitalization for observation and to rule out other conditions. (en)
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causes
| - Vaccination, most commonly pertussis vaccine. (en)
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has abstract
| - A hypotonic-hyporesponsive episode (HHE) is defined as sudden onset of poor muscle tone, , and pale or bluish skin occurring within 48 hours after vaccination, most commonly pertussis vaccination. An HHE is estimated to occur after 1 in 4,762 to 1 in 1,408 doses of whole cell pertussis vaccine, and after 1 in 14,286 to 1 in 2,778 doses of acellular pertussis vaccine. (en)
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differential
| - Vasovagal syncope, seizure (en)
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prevention
| - Those who experience an HHE after pertussis vaccination may avoid further pertussis vaccines. (en)
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symptoms
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