About: Hydroxypethidine

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Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is slightly more potent than meperidine as an analgesic, 1.5x meperidine in potency, and it also has NMDA antagonist properties like its close relative ketobemidone. Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:WikicatCarboxylateEsters yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:Chemical114806838 yago:Communication100033020 yago:Compound114818238 yago:Ester114850483 yago:Formula106816935 yago:Material114580897 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:OrganicCompound114727670 yago:Part113809207 yago:Phenol114989545 yago:PhysicalEntity100001930 yago:Relation100031921 drug yago:Statement106722453 yago:Substance100019613 yago:WikicatPhenols umbel-rc:DrugProduct
rdfs:label	Hydroxypethidine (en) Hydroksypetydyna (pl) Hydroxypetidin (sv)
rdfs:comment	Hydroksypetydyna – organiczny związek chemiczny, syntetyczny lek opioidowy objęty Jednolitą konwencją o środkach odurzających z 1961 roku (wykaz I). W Polsce jest w wykazie I-N Ustawy o przeciwdziałaniu narkomanii. (pl) Hydroxypetidin, C15H21NO, är ett smärtstillande preparat som tillhör gruppen opioider. Preparatet är 1,5 gånger mer potent än analogen petidin. Hydroxypetidin är narkotikaklassat och används inte som läkemedel i Sverige. (sv) Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is slightly more potent than meperidine as an analgesic, 1.5x meperidine in potency, and it also has NMDA antagonist properties like its close relative ketobemidone. Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening. (en)
foaf:depiction
dct:subject	4-Phenylpiperidines Carboxylate esters Mu-opioid receptor agonists Phenols Synthetic opioids
Wikipage page ID	10866207 (xsd:integer)
Wikipage revision ID	1082991735 (xsd:integer)
Link from a Wikipage to another Wikipage	Pethidine 4-Phenylpiperidines Carboxylate esters Mu-opioid receptor agonists Phenols Nausea 4-Fluoropethidine Analgesic Synthetic opioids Ketobemidone Opioid Itching Analog (chemistry) Respiratory depression NMDA antagonist
sameAs	Hydroxypethidine Hydroxypethidine Hydroxypethidine Hydroxypethidine Hydroxypethidine Hydroxypethidine Hydroxypethidine Hydroxypethidine Hydroxypethidine
dbp:wikiPageUsesTemplate	dbt:Analgesic-stub dbt:Drugbox dbt:Opioidergics dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Fdacite dbt:Stdinchicite
thumbnail	wiki-commons:Special:FilePath/hydroxypethidine.svg?width=300
ATC prefix	none (en)
c	15 (xsd:integer)
CAS number	468 (xsd:integer)
ChEBI	135085 (xsd:integer)
ChEMBL	1182665 (xsd:integer)
ChemSpiderID	55068 (xsd:integer)
H	21 (xsd:integer)
IUPAC name	Ethyl 4--1-methyl-piperidine-4-carboxylate (en)
legal DE	Anlage I (en)
legal US	Schedule I (en)
n	1 (xsd:integer)
O	3 (xsd:integer)
PubChem	61120 (xsd:integer)
SMILES	O=CC2CCNCC2 (en)
StdInChI	1 (xsd:integer)
StdInChIKey	WTJBNMUWRKPFRS-UHFFFAOYSA-N (en)
UNII	W1J43H2B3K (en)
verifiedrevid	447830929 (xsd:integer)
width	160 (xsd:integer)
has abstract	Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is slightly more potent than meperidine as an analgesic, 1.5x meperidine in potency, and it also has NMDA antagonist properties like its close relative ketobemidone. Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening. Hydroxypethidine is under international control under the Single Convention on Narcotic Drugs 1961 and therefore controlled like morphine in most countries; in the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9627 and a 2014 annual aggregate manufacturing quota of 2 grams. The salt in use is the hydrochloride, with a free base conversion ratio of 0.878. (en) Hydroksypetydyna – organiczny związek chemiczny, syntetyczny lek opioidowy objęty Jednolitą konwencją o środkach odurzających z 1961 roku (wykaz I). W Polsce jest w wykazie I-N Ustawy o przeciwdziałaniu narkomanii. (pl) Hydroxypetidin, C15H21NO, är ett smärtstillande preparat som tillhör gruppen opioider. Preparatet är 1,5 gånger mer potent än analogen petidin. Hydroxypetidin är narkotikaklassat och används inte som läkemedel i Sverige. (sv)
legal CA	Schedule I (en)
gold:hypernym	Analogue
prov:wasDerivedFrom	wikipedia-en:Hydroxypethidine?oldid=1082991735&ns=0

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