Henry Bryant Bigelow (October 3, 1879 – December 11, 1967) was an American oceanographer and marine biologist. He is the grandson of Henry Bryant who was an American physician and naturalist. After graduating from Harvard in 1901, he began working with famed ichthyologist Alexander Agassiz. Bigelow accompanied Agassiz on several major marine science expeditions including one aboard the Albatross in 1907. He began working at the Museum of Comparative Zoology in 1905 and joined Harvard's faculty in 1906 where he worked for 62 years.