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About: HLA-A     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Series108457976, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:Abstraction100002137yago:Allele105437785yago:Arrangement107938773yago:Gene105436752yago:Group100031264yago:Ordering108456993yago:WikicatGenesOnChromosome6yago:WikicatHLA-AAllelesBandHumanGeneyago:Sequence108459252yago:Series108457976 New Facet based on Instances of this Class

HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility complex (MHC) antigen specific to humans. HLA-A is one of three major types of human MHC class I transmembrane proteins. The others are HLA-B and HLA-C. The protein is a heterodimer, and is composed of a heavy α chain and smaller β chain. The α chain is encoded by a variant , and the β chain (β2-microglobulin) is an invariant β2 microglobulin molecule. The β2 microglobulin protein is encoded by the B2M gene, which is located at chromosome 15q21.1 in humans.