The Global Health Security Agenda (GHSA) is an international effort operating in the field of infection prevention and control. A brainchild of the Centers for Disease Control and Prevention (CDC), it was launched in February 2014 by a group of 44 countries and organizations including WHO. It was launched in 2014 as a five-year multilateral effort with the purpose to accelerate the implementation of the International Health Regulations (2005), particularly in developing countries. In 2017, GHSA was expanded to include non-state actors. It was also extended through 2024 with the release of the Global Health Security Agenda (GHSA) 2024 Framework (called “GHSA 2024”). The latter has the purpose to reach a standardized level of capacity to combat infectious diseases.