Gholam Hossein Sadighi (Persian: غلامحسین صدیقی; 3 December 1905 – 28 April 1991) was an Iranian politician and Minister of Interior in the government of Prime Minister Mohammad Mossadegh in 1953. After a CIA-backed coup d'etat overthrew Mossadegh, Sadighi was arrested and later testified in defense of Mossadegh at the latter's trial. Despite the loss of power, Sadighi continued to be politically active. He helped to found the Second National Front in 1960 and, along with other pro-Mossadegh politicians, advocated a democratic system and a Shah that reigns but does not rule.