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Fosaprepitant (Emend for Injection (US), Ivemend (EU)) is an antiemetic medication, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved for medical use in the United States, and in the European Union in January 2008.

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  • Fosaprepitant (en)
  • ホスアプレピタント (ja)
  • 福沙匹坦 (zh)
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  • Fosaprepitant (Emend for Injection (US), Ivemend (EU)) is an antiemetic medication, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved for medical use in the United States, and in the European Union in January 2008. (en)
  • ホスアプレピタント メグルミン(Fosaprepitant Meglumine)は静脈注射で用いられる制吐剤の一つである。アプレピタントのプロドラッグにあたる。商品名プロイメンド。 2008年1月に米国でFDAに承認され、2008年1月に欧州でもEMAに承認された。日本では2011年9月に承認された。 (ja)
  • 福沙匹坦(Fosaprepitant)是一種肿瘤用药,用于肿瘤治疗过程中,化疗的辅助用药,防止化疗引起的恶心、呕吐。化学特征為阿瑞匹坦的磷酸酯前药。在美国的商品名为Emend,在欧洲的商品名为Ivmend。福沙匹坦是由默克公司开发上市的药物,美国食品药品监督管理局(FDA)在2008年1月25日批准其上市,同年1月11日,欧洲药物管理局(EMA)批准其上市销售。 (zh)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Fosaprepitant-3D-spacefill.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Fosaprepitant.svg
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ATC suffix
  • AD12 (en)
alt
  • Skeletal formula of fosaprepitant (en)
  • Space-filling model of the fosaprepitant molecule (en)
ATC prefix
  • A04 (en)
bioavailability
  • n/a (en)
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DrugBank
  • DB06717 (en)
elimination half-life
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  • Fosaprepitant-3D-spacefill.png (en)
IUPAC name
  • [3-{[-2-[-1-[3,5-bisphenyl] ethoxy]-3-morpholin-4-yl]methyl}-5-oxo- 2H-1,2,4-triazol-1-yl]phosphonic acid (en)
KEGG
  • D06597 (en)
legal UK
  • POM (en)
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