State Road 50 (SR 50) runs across the center of the U.S. state of Florida through Orlando, with its termini at SR 55 (US 19) at Weeki Wachee and SR 5 (U.S. Route 1) in Titusville. SR 50 is signed east–west. Within various counties throughout the state, the highway is signed with various names such as Cortez Boulevard in Hernando County and Colonial Drive in Orange County. The former section includes the concurrency with US 98 between Brooksville and near Ridge Manor. US 98-SR 50 is the only interchange with Interstate 75 in Hernando County.