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Fipexide (Attentil, Vigilor) is a psychoactive drug of the piperazine chemical class which was developed in Italy in 1983. It was used as a nootropic drug in Italy and France, mainly for the treatment of senile dementia, but is no longer in common use due to the occurrence of rare adverse drug reactions including fever and hepatitis. Fipexide is similar in action to other nootropic drugs such as piracetam and has a few similarities in chemical structure to centrophenoxine. Chemically, it is an amide union of parachlorophenoxyacetate and methylenedioxybenzylpiperazine (MDBZP), and has been shown to metabolize to the latter, which plays a significant role in its effects.

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  • Fipexida (es)
  • Fipexide (en)
  • Fipexide (it)
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  • Fipexide (Attentil, Vigilor) is a psychoactive drug of the piperazine chemical class which was developed in Italy in 1983. It was used as a nootropic drug in Italy and France, mainly for the treatment of senile dementia, but is no longer in common use due to the occurrence of rare adverse drug reactions including fever and hepatitis. Fipexide is similar in action to other nootropic drugs such as piracetam and has a few similarities in chemical structure to centrophenoxine. Chemically, it is an amide union of parachlorophenoxyacetate and methylenedioxybenzylpiperazine (MDBZP), and has been shown to metabolize to the latter, which plays a significant role in its effects. (en)
  • Il fipexide è un farmaco derivato dalla piperazina inventato in Italia nel 1983. Il fipexide è simile in azione nootropica ad altri farmaci quali il piracetam e ha una struttura simile ad un altro più noto nootropico, il . È stato utilizzato come farmaco nootropo in Francia e in Italia, principalmente per il trattamento della demenza senile con dei risultati eccezionali ma non è più in uso comune a causa di una accusa delle case farmeceutiche statunitensi su delle presunte rare reazioni avverse al farmaco tra cui episodi di febbre ed epatite. (it)
  • La Fipexida (conocida también por sus marcas comerciales Attentil y Vigilor) es una medicamento psicoactivo de la clase química de las piperazinas, desarrollada en Italia en 1983.​ Se utiliza como nootrópico en Italia y Francia, principalmente para el tratamiento de la demencia senil,​ pero ya no es de uso común debido a la ocurrencia de raras reacciones adversas, incluyendo fiebre y hepatitis. La fipexida tiene acción similar a otros fármacos nootrópicos como el piracetam, y es estructuralmente similar a otro conocido nootrópico, la centrofenoxina. Químicamente, es una unión amídica de paraclorofenoxiacetato y metil-enedi-oxi-benzil-piperazina, y en particular, se ha demostrado que metabolizan a este último, que desempeña un papel significativo en sus efectos. (es)
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  • BX05 (en)
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  • N06 (en)
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