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Figitumumab (previously CP-751871) is a monoclonal antibody targeting the insulin-like growth factor-1 receptor that was investigated for the treatment of various types of cancer, for example adrenocortical carcinoma and non-small cell lung cancer (NSCLC). This drug was being developed by Pfizer, but they ceased development of the drug in January 2011 and has stopped its manufacture.

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rdf:type
rdfs:label
  • فيجيتوموماب (ar)
  • Figitumumab (en)
  • Figitumumab (it)
rdfs:comment
  • فيجيتوموماب (بالإنجليزية: Figitumumab)‏ هو جسم مضاد وحيد النسيلة أجريت عليه التجارب السريرية لعلاج عدد من أنواع السرطان مثل سرطانة القشرة الكظرية وسرطانة الرئة غير صغيرة الخلايا. فيجيتوموماب طورته فايزر. علّقت المرحلة الثالثة من التجارب السريرية لعلاج سرطانة خلايا الرئة غير الصغيرة في كانون الأول 2009 بسبب حالات الوفيات المرتفعة، لكن بقيت الدراسات استمرت. التجارب السريرية لاستخدامه في علاج سرطان الثدي بدأت بعد ذلك. (ar)
  • Figitumumab (previously CP-751871) is a monoclonal antibody targeting the insulin-like growth factor-1 receptor that was investigated for the treatment of various types of cancer, for example adrenocortical carcinoma and non-small cell lung cancer (NSCLC). This drug was being developed by Pfizer, but they ceased development of the drug in January 2011 and has stopped its manufacture. (en)
  • Il figitumumab o CP-751871 è un anticorpo monoclonale di tipo umano, che è stato testato nel trattamento di varie forme di tumore come: il carcinoma del surrene e il tumore del polmone non a piccole cellule. Esso agisce sul recettore per IGF-1 (Insulin-like growth factor 1) o che è noto avere un ruolo nello sviluppo di alcuni tumori. Il farmaco è sviluppato dalla Pfizer. (it)
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  • none (en)
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  • none (en)
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KEGG
  • D09345 (en)
legal status
  • Experimental (en)
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  • mab (en)
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  • VE267FC2UB (en)
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  • فيجيتوموماب (بالإنجليزية: Figitumumab)‏ هو جسم مضاد وحيد النسيلة أجريت عليه التجارب السريرية لعلاج عدد من أنواع السرطان مثل سرطانة القشرة الكظرية وسرطانة الرئة غير صغيرة الخلايا. فيجيتوموماب طورته فايزر. علّقت المرحلة الثالثة من التجارب السريرية لعلاج سرطانة خلايا الرئة غير الصغيرة في كانون الأول 2009 بسبب حالات الوفيات المرتفعة، لكن بقيت الدراسات استمرت. التجارب السريرية لاستخدامه في علاج سرطان الثدي بدأت بعد ذلك. (ar)
  • Figitumumab (previously CP-751871) is a monoclonal antibody targeting the insulin-like growth factor-1 receptor that was investigated for the treatment of various types of cancer, for example adrenocortical carcinoma and non-small cell lung cancer (NSCLC). This drug was being developed by Pfizer, but they ceased development of the drug in January 2011 and has stopped its manufacture. (en)
  • Il figitumumab o CP-751871 è un anticorpo monoclonale di tipo umano, che è stato testato nel trattamento di varie forme di tumore come: il carcinoma del surrene e il tumore del polmone non a piccole cellule. Esso agisce sul recettore per IGF-1 (Insulin-like growth factor 1) o che è noto avere un ruolo nello sviluppo di alcuni tumori. Il farmaco è sviluppato dalla Pfizer. Il suo ruolo come farmaco antineoplastico è ancora controverso. Alla fine del 2009 la Pfizer ha interrotto uno studio di fase 3 sul carcinoma polmonare non a piccole cellule, per la scarsa significatività del risultato in termini di sopravvivenza. (it)
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  • 943453-46-1
FDA UNII code
  • VE267FC2UB
KEGG
  • D09345
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