The Epstein–Barr virus nuclear antigen 3 (EBNA-3) is a family of viral proteins associated with the Epstein–Barr virus. A typical EBV genome contains three such proteins:
* EBNA-3A (P12977, EBNA-3; BLRF3-BERF1)
* EBNA-3B (P03203, EBNA-4; BERF2A-BERF2B)
* EBNA-3C (P03204, EBNA-6, EBNA-4B; BERF3-BERF4) These genes also bind the host RBP-Jκ protein. EBNA-3C can recruit a ubiquitin ligase and has been shown to target cell-cycle regulators such as retinoblastoma protein (pRb).
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| - EBV antígeno nuclear 3 (es)
- Epstein–Barr virus nuclear antigen 3 (en)
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| - The Epstein–Barr virus nuclear antigen 3 (EBNA-3) is a family of viral proteins associated with the Epstein–Barr virus. A typical EBV genome contains three such proteins:
* EBNA-3A (P12977, EBNA-3; BLRF3-BERF1)
* EBNA-3B (P03203, EBNA-4; BERF2A-BERF2B)
* EBNA-3C (P03204, EBNA-6, EBNA-4B; BERF3-BERF4) These genes also bind the host RBP-Jκ protein. EBNA-3C can recruit a ubiquitin ligase and has been shown to target cell-cycle regulators such as retinoblastoma protein (pRb). (en)
- EBV antígeno nuclear 3 es una familia de las proteínas virales asociadas con el virus de Epstein-Barr.
* EBNA-3A
* EBNA-3B
* EBNA-3C Estos genes también se unen al anfitrión de las proteínas RBP-Jκ. EBNA-3C puede contratar a una ubiquitina-ligasa y se ha demostrado que el objetivo reguladores del ciclo celular como pRb. (es)
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| - The Epstein–Barr virus nuclear antigen 3 (EBNA-3) is a family of viral proteins associated with the Epstein–Barr virus. A typical EBV genome contains three such proteins:
* EBNA-3A (P12977, EBNA-3; BLRF3-BERF1)
* EBNA-3B (P03203, EBNA-4; BERF2A-BERF2B)
* EBNA-3C (P03204, EBNA-6, EBNA-4B; BERF3-BERF4) These genes also bind the host RBP-Jκ protein. EBNA-3C can recruit a ubiquitin ligase and has been shown to target cell-cycle regulators such as retinoblastoma protein (pRb). (en)
- EBV antígeno nuclear 3 es una familia de las proteínas virales asociadas con el virus de Epstein-Barr.
* EBNA-3A
* EBNA-3B
* EBNA-3C Estos genes también se unen al anfitrión de las proteínas RBP-Jκ. EBNA-3C puede contratar a una ubiquitina-ligasa y se ha demostrado que el objetivo reguladores del ciclo celular como pRb. (es)
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