Edward Frederick Clarke (April 24, 1850 – March 3, 1905) was a Canadian journalist and political figure. He was Mayor of Toronto for four one-year terms, from 1888 until 1891 while also representing Toronto in the Legislative Assembly of Ontario from 1886 to 1894 and West Toronto from 1896 to 1904 and Toronto Centre from 1904 to 1905 in the House of Commons of Canada as a Conservative member. He attempted to regain the mayoralty in 1900 but was defeated by Ernest A. Macdonald. He was also a member of the Orange Order in Canada.