Edward Nicholas Anderson (November 11, 1900 – April 24, 1974) was an American football player and coach of football and basketball. He served as the head football coach at Columbia College in Dubuque, Iowa, now known as Loras College (1922–1924), DePaul University (1925–1931), the College of the Holy Cross (1933–1938, 1950–1964), and the University of Iowa (1939–1942, 1946–1949), compiling a career college football record of 201–128–15. Anderson was also the head basketball coach at DePaul from 1925 to 1929, tallying a mark of 25–21. Anderson played professional football in the National Football League (NFL) for the Rochester Jeffersons in 1922 and the Chicago Cardinals from 1922 to 1925. He was inducted into the College Football Hall of Fame as a coach in 1971.