Drosophila X virus (DXV) belongs to the Birnaviridae family of viruses. Birnaviridae currently consists of three genera. The first genus is Entomobirnavirus, which contains DXV. The next genus is Aquabirnavirus, containing infectious pancreatic necrosis virus (IPNV). The last genus is Avibirnavirus, which contains infectious bursal disease virus (IBDV). All of these genera contain homology in three specific areas of their transcripts. The homology comes from the amino and carboxyl regions of preVP2, a small 21-residue-long domain near the carboxyl terminal of VP3, and similar small ORFs sequences.
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| - Drosophila X virus (en)
- Drosophila-X-Virus (de)
- ショウジョウバエXウイルス (ja)
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| - ショウジョウバエXウイルス(Drosophila X virus)は、ショウジョウバエに感染するビルナウイルス科のウイルスである。モデル生物であるキイロショウジョウバエのを研究するのによく用いられる。カプシドはおおよそ六方晶状で、20面体対称である。ウイルスのゲノムは、2本の線状の2本鎖RNAから構成される。そのため、このウイルスはしばしば感染機構としてのRNAiの研究に用いられる。 研究室では広く用いられるが、ショウジョウバエXウイルスが自然界で ショウジョウバエに感染したものは発見されていない。当初は研究室の培養細胞の中から発見された。 (ja)
- Drosophila X virus (DXV) belongs to the Birnaviridae family of viruses. Birnaviridae currently consists of three genera. The first genus is Entomobirnavirus, which contains DXV. The next genus is Aquabirnavirus, containing infectious pancreatic necrosis virus (IPNV). The last genus is Avibirnavirus, which contains infectious bursal disease virus (IBDV). All of these genera contain homology in three specific areas of their transcripts. The homology comes from the amino and carboxyl regions of preVP2, a small 21-residue-long domain near the carboxyl terminal of VP3, and similar small ORFs sequences. (en)
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| - Drosophila X virus (DXV) belongs to the Birnaviridae family of viruses. Birnaviridae currently consists of three genera. The first genus is Entomobirnavirus, which contains DXV. The next genus is Aquabirnavirus, containing infectious pancreatic necrosis virus (IPNV). The last genus is Avibirnavirus, which contains infectious bursal disease virus (IBDV). All of these genera contain homology in three specific areas of their transcripts. The homology comes from the amino and carboxyl regions of preVP2, a small 21-residue-long domain near the carboxyl terminal of VP3, and similar small ORFs sequences. DXV was named after Drosophila melanogaster, where it was first isolated. DXV was first isolated and named in 1978. DXV was discovered as a contaminant in adult D. melanogaster while studying rhabdoviruses. Assay results of DXV showed that DXV induces sensitivity to both carbon dioxide and NH2, which suggests general anoxia. Therefore, the pathogenic pathway for DXV leads to anoxia sensitivity and death of D. melanogaster. By negative contrast electron microscopy the DXV components were first visualized. The origin of DXV is unknown and unclear. It was thought that DXV could have been pre-existent in Drosophila broods in a non-pathogenic form. Additionally, it was speculated that DXV might have originated as a contaminant from fetal calf serum in infection type studies because it was documented that endogenous bovine viruses were already in fetal calf serum. (en)
- ショウジョウバエXウイルス(Drosophila X virus)は、ショウジョウバエに感染するビルナウイルス科のウイルスである。モデル生物であるキイロショウジョウバエのを研究するのによく用いられる。カプシドはおおよそ六方晶状で、20面体対称である。ウイルスのゲノムは、2本の線状の2本鎖RNAから構成される。そのため、このウイルスはしばしば感染機構としてのRNAiの研究に用いられる。 研究室では広く用いられるが、ショウジョウバエXウイルスが自然界で ショウジョウバエに感染したものは発見されていない。当初は研究室の培養細胞の中から発見された。 (ja)
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