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In molecular biology, DisProt is a curated biological database collection of intrinsically unstructured proteins. It is a community resource annotating protein sequences for intrinsically disorder regions from the literature. DisProt classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partners.

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  • DisProt
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  • In molecular biology, DisProt is a curated biological database collection of intrinsically unstructured proteins. It is a community resource annotating protein sequences for intrinsically disorder regions from the literature. DisProt classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partners.
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dc:description
  • DisProt contains information and disorder annotation in intrinsically unstructured proteins.
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pmid
curation
  • Yes - manual curation from the literature
download
webservice
  • REST API see info
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Description
  • DisProt contains information and disorder annotation in intrinsically unstructured proteins.
format
  • CVS and JSON
license
logo
Organism
  • All
released
  • September 2019
scope
  • Annotation of intrinsically unstructured proteins
title
  • DisProt
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version
Center
  • Department of Biomedical Sciences at University of Padua
has abstract
  • In molecular biology, DisProt is a curated biological database collection of intrinsically unstructured proteins. It is a community resource annotating protein sequences for intrinsically disorder regions from the literature. DisProt classifies intrinsic disorder based on experimental methods and three ontologies for molecular function, transition and binding partners. Historically, the study of disordered proteins has been hampered by the lack of an organised resource collecting them and their properties together. Release 7 of DisProt contains information on more than 800 proteins. Each protein entry in DisProt is characterised by a DisProt identifier which takes the form of the prefix DP followed by a 5 digit protein identifier. For example, DP00016 refers to the Cyclin-dependent kinase inhibitor 1 protein. Release 8 of DisProt contains more than 1400 non ambiguous entries and over 3000 disordered protein regions. DisProt 8 also introduced the concept of a stable DisProt region identifier. DisProt has been widely used to train software methods to predict disordered regions in proteins. In addition, DisProt has been used to understand the properties of intrinsically unstructured proteins.
title
  • DisProt
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