Derek Rain Thompson (born January 8, 1981) is a former Major League Baseball pitcher. He was drafted by the Cleveland Indians in the 1st round of the 2000 Major League Baseball Draft and pitched in the Indians minor league system for the Burlington Indians (2000), Columbus Indians (2001–2002) and Kinston Indians (2002). He was drafted by the Chicago Cubs in the Rule 5 draft on December 16, 2002, and then sold to the Los Angeles Dodgers. For the Dodgers he played for the Jacksonville Suns in 2004 & 2005, appearing in the Southern League All-Star Game in 2004.