Daf-5 is an ortholog of the mammalian protein Sno/Ski,which present in the nematode worm Caenorhabditis elegans on the downstream of TGFβ signaling pathway. Without daf-7 signal, daf-5 combined with daf-3, co-SMAD for C. elegans, to form a heterodimer and started dauer development.
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