Colubrina greggii is a species of flowering plant in the family Rhamnaceae, that is commonly known as the Sierra nakedwood or Gregg's colubrina. It is native to eastern Mexico, with a disjunct population in southern Texas in the United States. It is very similar to of Southern Florida and the Caribbean, and herbarium specimens of the two species are difficult to distinguish. The name honours American botanist Josiah Gregg (1806 – 1850), who collected the holotype near Monterrey, Nuevo León in 1848.