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In the field of drug discovery, classical pharmacology, also known as forward pharmacology, or phenotypic drug discovery (PDD), relies on phenotypic screening (screening in intact cells or whole organisms) of chemical libraries of synthetic small molecules, natural products or extracts to identify substances that have a desirable therapeutic effect. Using the techniques of medicinal chemistry, the potency, selectivity, and other properties of these screening hits are optimized to produce candidate drugs.

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  • Classical pharmacology
  • Farmacología clásica
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  • En el campo del descubrimiento de fármacos, la farmacología clásica,​ también conocida como farmacología avanzada,​​​ o descubrimiento de fármacos fenotípicos (PDD),​ basa en la detección fenotípica (detección en células intactas o en organismos multicelulares) de de pequeñas moléculas sintéticas, productos naturales o extractos para identificar sustancias que tienen un efecto terapéutico deseable. El uso de las técnicas de química médica, la potencia, la selectividad y otras propiedades de estos éxitos de detección se optimizan para producir fármacos candidatos.
  • In the field of drug discovery, classical pharmacology, also known as forward pharmacology, or phenotypic drug discovery (PDD), relies on phenotypic screening (screening in intact cells or whole organisms) of chemical libraries of synthetic small molecules, natural products or extracts to identify substances that have a desirable therapeutic effect. Using the techniques of medicinal chemistry, the potency, selectivity, and other properties of these screening hits are optimized to produce candidate drugs.
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  • En el campo del descubrimiento de fármacos, la farmacología clásica,​ también conocida como farmacología avanzada,​​​ o descubrimiento de fármacos fenotípicos (PDD),​ basa en la detección fenotípica (detección en células intactas o en organismos multicelulares) de de pequeñas moléculas sintéticas, productos naturales o extractos para identificar sustancias que tienen un efecto terapéutico deseable. El uso de las técnicas de química médica, la potencia, la selectividad y otras propiedades de estos éxitos de detección se optimizan para producir fármacos candidatos.
  • In the field of drug discovery, classical pharmacology, also known as forward pharmacology, or phenotypic drug discovery (PDD), relies on phenotypic screening (screening in intact cells or whole organisms) of chemical libraries of synthetic small molecules, natural products or extracts to identify substances that have a desirable therapeutic effect. Using the techniques of medicinal chemistry, the potency, selectivity, and other properties of these screening hits are optimized to produce candidate drugs.
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