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About: Chem-seq     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatProteinMethods, within Data Space : dbpedia.org associated with source document(s)

Type: topical conceptyago:WikicatMolecularBiologyTechniquesyago:Ability105616246yago:Abstraction100002137yago:Cognition100023271yago:Know-how105616786yago:Method105660268yago:PsychologicalFeature100023100yago:Technique105665146yago:WikicatProteinMethods New Facet based on Instances of this Class

Chem-seq is a technique that is used to map genome-wide interactions between small molecules and their protein targets in the chromatin of eukaryotic cell nuclei. The method employs chemical affinity capture coupled with massively parallel DNA sequencing to identify genomic sites where small molecules interact with their target proteins or DNA. It was first described by Lars Anders et al. in the January, 2014 issue of "Nature Biotechnology".