Central Medford High School (formerly Medford Opportunity High School) is a public alternative high school in Medford, Oregon, United States. In 2010 the school moved from its original location on Earhart Street to a new location on Oakdale Avenue in Medford. It occupied part of the old South Medford High School (which is now located on Cunningham Avenue in Medford). In 2020 the school relocated to its current location on Royal Avenue in Medford, occupying the previous location of Grace Christian campus.