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About: Cap formation     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:YagoPermanentlyLocatedEntity, within Data Space : dbpedia.org associated with source document(s)

Type: yago:WikicatCellularProcessesyago:Abstraction100002137yago:Act100030358yago:Activity100407535yago:Event100029378yago:Procedure101023820yago:PsychologicalFeature100023100yago:YagoPermanentlyLocatedEntity New Facet based on Instances of this Class

When molecules on the surface of a motile eukaryotic cell are crosslinked, they are moved to one end of the cell to form a "cap". This phenomenon, the process of which is called cap formation, was discovered in 1971 on lymphocytes and is a property of amoebae and all locomotory animal cells except sperm. The crosslinking is most easily achieved using a polyvalent antibody to a surface antigen on the cell. Cap formation can be visualised by attaching a fluorophore, such as fluorescein, to the antibody.