About: Candicidin

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Candicidin is an antifungal compound obtained from Streptomyces griseus. It is active against some fungi including Candida albicans. Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis. This bioactive compound was named candicidin, because of its high activity on Candida albicans.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Pill (pharmacy) yago:WikicatAntifungals yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:Agent114778436 yago:Antifungal102720201 yago:CausalAgent100007347 yago:Communication100033020 yago:Formula106816935 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:PhysicalEntity100001930 chemical compound drug yago:Statement106722453 yago:Substance100020090 umbel-rc:DrugProduct
rdfs:label	Candicidin (de) Candicidin (en) Candicidina (it)
rdfs:comment	Candicidin ist ein aus vier Komponenten bestehendes Antibiotikum. Die Hauptkomponente, Candicidin D, ist eine chemische Verbindung aus der Gruppe der Makrolide und Heptaene. Candicidin wurde zuerst 1953 von Lechevalier beschrieben und nach seiner Wirkung gegen Candida-Pilze benannt. (de) Candicidin is an antifungal compound obtained from Streptomyces griseus. It is active against some fungi including Candida albicans. Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis. This bioactive compound was named candicidin, because of its high activity on Candida albicans. (en) Candicidina (nella fase sperimentale conosciuta anche con la sigla Cl35) è un antibiotico un lattone macrociclico (macrolide) costituito da una miscela di eptaeni prodotti da Streptomyces griseus. Il composto venne isolato durante l'estate del 1948 presso il Rutgers University Institute of Microbiology a partire da del letame di vacca.Il farmaco è attivo contro alcuni lieviti e funghi simili a lieviti, ma non sui funghi filamentosi. È invece sprovvisto di attività antibatterica.La molecola è particolarmente attiva verso Candida albicans: il suo nome deriva dall'elevata azione contro questo fungo. Lo spettro di assorbimento della luce del composto lo rende simile ad , e lo distingue da nistatina e . (it)
foaf:depiction
dcterms:subject	Polyenes Macrolides Antifungals
Wikipage page ID	14622192 (xsd:integer)
Wikipage revision ID	1094134052 (xsd:integer)
Link from a Wikipage to another Wikipage	Candidiasis Streptomyces griseus Polyenes Bioactive compounds Macrolides Antifungals Candida albicans Antifungal medication
sameAs	Candicidin Candicidin Candicidin Candicidin Candicidin Candicidin Candicidin Candicidin Candicidin Candicidin
dbp:wikiPageUsesTemplate	dbt:Gynecological_anti-infectives_and_antiseptics dbt:Drugbox dbt:Genito-urinary-drug-stub dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Stdinchicite
thumbnail	wiki-commons:Special:FilePath/Candicidin.png?width=300
ATC suffix	AA04 (en)
ATC prefix	G01 (en)
c	59 (xsd:integer)
CAS number	1403 (xsd:integer)
ChEMBL	1200647 (xsd:integer)
ChemSpiderID	10128184 (xsd:integer)
DrugBank	DB01152 (en)
H	84 (xsd:integer)
IUPAC name	33 (xsd:integer)
n	2 (xsd:integer)
O	18 (xsd:integer)
PubChem	441142 (xsd:integer)
SMILES	Nc1cccCCCCCCC3OCCCCCCCCCCCCCCC4CCCCO4 (en)
StdInChI	1 (xsd:integer)
StdInChIKey	YKSVGLFNJPQDJE-WDANKXQLSA-N (en)
UNII	48 (xsd:integer)
Verifiedfields	changed (en)
verifiedrevid	460122980 (xsd:integer)
Watchedfields	changed (en)
has abstract	Candicidin ist ein aus vier Komponenten bestehendes Antibiotikum. Die Hauptkomponente, Candicidin D, ist eine chemische Verbindung aus der Gruppe der Makrolide und Heptaene. Candicidin wurde zuerst 1953 von Lechevalier beschrieben und nach seiner Wirkung gegen Candida-Pilze benannt. (de) Candicidin is an antifungal compound obtained from Streptomyces griseus. It is active against some fungi including Candida albicans. Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis. This bioactive compound was named candicidin, because of its high activity on Candida albicans. (en) Candicidina (nella fase sperimentale conosciuta anche con la sigla Cl35) è un antibiotico un lattone macrociclico (macrolide) costituito da una miscela di eptaeni prodotti da Streptomyces griseus. Il composto venne isolato durante l'estate del 1948 presso il Rutgers University Institute of Microbiology a partire da del letame di vacca.Il farmaco è attivo contro alcuni lieviti e funghi simili a lieviti, ma non sui funghi filamentosi. È invece sprovvisto di attività antibatterica.La molecola è particolarmente attiva verso Candida albicans: il suo nome deriva dall'elevata azione contro questo fungo. Lo spettro di assorbimento della luce del composto lo rende simile ad , e lo distingue da nistatina e . (it)
gold:hypernym	Compound
prov:wasDerivedFrom	wikipedia-en:Candicidin?oldid=1094134052&ns=0
page length (characters) of wiki page	3586 (xsd:nonNegativeInteger)
CAS number	1403-17-4
ChEMBL	1200647
DrugBank	DB01152
FDA UNII code	48N2IYJ202
PubChem	441142
foaf:isPrimaryTopicOf	wikipedia-en:Candicidin
is Link from a Wikipage to another Wikipage of	FR-008-III List of compounds with carbon numbers 50+ Antifungal List of MeSH codes (D02) Polyene Rutgers University dbr:Streptomycin

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