The Dr. William Barrow Mansion is located at 83 Wayne Street between Barrow Street and Jersey Avenue in Downtown Jersey City, Hudson County, New Jersey, United States. The mansion was added to the National Register of Historic Places on May 2, 1977, and is located within the Van Vorst Park Historic District, which itself was dedicated on March 5, 1980, and is roughly bounded by Railroad Avenue, and Henderson, Grand, Bright, and Monmouth Streets.