Artemether is a medication used for the treatment of malaria. The injectable form is specifically used for severe malaria rather than quinine. In adults, it may not be as effective as artesunate. It is given by injection in a muscle. It is also available by mouth in combination with lumefantrine, known as artemether/lumefantrine. Artemether has been studied since at least 1981, and been in medical use since 1987. It is on the World Health Organization's List of Essential Medicines.