Annetto Casolani (10 August 1815 - 1 August 1866) was a Maltese prelate who served as the first Apostolic Vicar of Central Africa present day Archdiocese of Khartoum in Sudan. Casolani was born in Valletta Malta on 10 August 1815. His father was Sir Vincent Casolani who served as a high ranking government official. He started his studies at the University of Malta and continued at the Seminario Romano in Rome where he obtained a Doctorate in Divinity. While still a seminarian, he was appointed a Canon of the Cathedral Chapter of Mdina. He was later promoted to the dignity of Cantor in 1837. After 2 years, he entered the Collegio Urbano for further studies in Theology and Oriental languages.