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About: Analytical ultracentrifugation     Goto   Sponge   NotDistinct   Permalink

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Analytical ultracentrifugation is an analytical technique which combines an ultracentrifuge with optical monitoring systems. In an analytical ultracentrifuge (commonly abbreviated as AUC), a sample’s sedimentation profile is monitored in real time by an optical detection system. The sample is detected via ultraviolet light absorption and/or interference optical refractive index sensitive system. The operator can thus observe the evolution of sample concentration versus the axis of the rotation profile as a result of the applied centrifugal field. With modern instrumentation, these observations are electronically digitized and stored for further mathematical analysis.