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About: Almitrine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatMolecularFormulasyago:Abstraction100002137yago:Agent109190918yago:Agent114778436yago:CausalAgent100007347yago:Communication100033020yago:Drug103247620yago:Formula106816935yago:Matter100020827yago:Medicine103740161yago:Message106598915yago:MolecularFormula106817173yago:PhysicalEntity100001930yago:Piperazine103946814drugyago:Statement106722453yago:Substance100020090yago:Vermifuge104528630yago:WikicatPiperazinesyago:WikicatRespiratoryAgentsumbel-rc:DrugProduct New Facet based on Instances of this Class

Almitrine (marketed as Duxil by Servier) is a diphenylmethylpiperazine derivative classified as a respiratory stimulant by the ATC. It enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.A significant literature exists for this compound, including over 60 papers that Medline labels as reviews.