Alexander Sergeevich Spirin (Russian: Александр Сергеевич Спирин) (4 September 1931 – 30 December 2020) was a Russian biochemist, Distinguished Professor at the Lomonosov Moscow State University (since 1999), a Director of , Puschino (Пущино-на-Оке), Moscow Region (Московская Область), Academician of Russian Academy of Sciences. His primary scientific interests in biochemistry included nucleic acids and protein biosynthesis.