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Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. Trovafloxacin and alatrofloxacin were both withdrawn from the U.S. market in June 2006 due to hepatotoxicity leading to liver transplant or death.

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  • ألاتروفلوكساسين (ar)
  • Alatrofloxacin (en)
  • Alatrofloxacina (it)
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  • ألاتروفلوكساسين (alatrofloxacin) (ar)
  • Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. Trovafloxacin and alatrofloxacin were both withdrawn from the U.S. market in June 2006 due to hepatotoxicity leading to liver transplant or death. (en)
  • L' alatrofloxacina è un principio attivo che appartiene alla classe dei chinoloni di quarta generazione. È un profarmaco della trovafloxacina. Il farmaco è stato commercializzato in UE dalla società farmaceutica Pfizer con il nome di Trovan IV, nella forma di sale mesilato. Il 20 marzo 2001, la Commissione Europea ha adottato la decisione di ritirare l'autorizzazione al commercio del farmaco. Il farmaco era già stato sospeso nell'agosto 1999 dopo la segnalazione di 152 casi documentati di eventi seri di epatite, inclusi 9 casi di decesso o che avevano richiesto un trapianto di fegato. (it)
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  • none (en)
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  • N/A (en)
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  • Fecal and renal (en)
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  • Withdrawn (en)
MedlinePlus
  • a605016 (en)
metabolism
  • Quickly hydrolyzed to trovafloxacin (en)
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  • C (en)
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  • ألاتروفلوكساسين (alatrofloxacin) (ar)
  • Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. Trovafloxacin and alatrofloxacin were both withdrawn from the U.S. market in June 2006 due to hepatotoxicity leading to liver transplant or death. (en)
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