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Aclarubicin (INN) or aclacinomycin A is an anthracycline drug that is used in the treatment of cancer. Soil bacteria Streptomyces galilaeus can produce aclarubicin. It can induce histone eviction from chromatin upon intercalation.

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rdf:type
rdfs:label
  • Aclarubicin (en)
  • アクラルビシン (ja)
rdfs:comment
  • Aclarubicin (INN) or aclacinomycin A is an anthracycline drug that is used in the treatment of cancer. Soil bacteria Streptomyces galilaeus can produce aclarubicin. It can induce histone eviction from chromatin upon intercalation. (en)
  • アクラルビシン(Aclarubicin)またはアクラシノマイシンA(Aclacinomycin A)は、悪性腫瘍の治療に用いられるアントラサイクリン系の抗腫瘍性抗生物質である。土壌細菌 により産生される。インターカレーションにより、クロマチンからヒストンの脱離を誘導する事が出来る。 (ja)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Aclarubicin.svg
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ATC suffix
  • DB04 (en)
ATC prefix
  • L01 (en)
c
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H
IUPAC name
  • -Methyl 4--2-ethyl-2,5,7-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate (en)
KEGG
  • D02756 (en)
legal status
  • Rx-only (en)
melting high
melting point
n
O
PubChem
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SMILES
  • CCC1O (en)
StdInChI
StdInChIKey
  • USZYSDMBJDPRIF-UHFFFAOYSA-N (en)
UNII
Verifiedfields
  • changed (en)
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  • changed (en)
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  • Aclarubicin (INN) or aclacinomycin A is an anthracycline drug that is used in the treatment of cancer. Soil bacteria Streptomyces galilaeus can produce aclarubicin. It can induce histone eviction from chromatin upon intercalation. (en)
  • アクラルビシン(Aclarubicin)またはアクラシノマイシンA(Aclacinomycin A)は、悪性腫瘍の治療に用いられるアントラサイクリン系の抗腫瘍性抗生物質である。土壌細菌 により産生される。インターカレーションにより、クロマチンからヒストンの脱離を誘導する事が出来る。 (ja)
melting notes
  • (en)
gold:hypernym
prov:wasDerivedFrom
page length (characters) of wiki page
CAS number
  • 57576-44-0
ChEBI
  • 74619
ChEMBL
  • 502620
FDA UNII code
  • 74KXF8I502
KEGG
  • D02756
PubChem
  • 42474
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