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AAA proteins or ATPases Associated with diverse cellular Activities are a protein family sharing a common conserved module of approximately 230 amino acid residues. This is a large, functionally diverse protein family belonging to the AAA+ protein superfamily of ring-shaped P-loop NTPases, which exert their activity through the energy-dependent remodeling or translocation of macromolecules. AAA proteins couple chemical energy provided by ATP hydrolysis to conformational changes which are transduced into mechanical force exerted on a macromolecular substrate.

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  • AAA proteins
  • Protéines AAA
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  • AAA proteins or ATPases Associated with diverse cellular Activities are a protein family sharing a common conserved module of approximately 230 amino acid residues. This is a large, functionally diverse protein family belonging to the AAA+ protein superfamily of ring-shaped P-loop NTPases, which exert their activity through the energy-dependent remodeling or translocation of macromolecules. AAA proteins couple chemical energy provided by ATP hydrolysis to conformational changes which are transduced into mechanical force exerted on a macromolecular substrate.
  • Les protéines AAA ou ATPases Associées à diverses Activités cellulaires constituent une famille de protéines qui partagent un domaine conservé commun d'environ 230 acides aminés de long. Il s'agit d'une grande famille protéique fonctionnellement diverse, appartenant à la superfamille protéique AAA+ des NTPases en motifs de Walker en forme d'anneaux, qui exercent leur activité par la reconstruction (consommant de l'énergie) ou la translocation de macromolécules.
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  • ATPases associated with diverse cellular activities
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