7-carboxy-7-deazaguanine synthase (EC 4.3.99.3, 7-carboxy-7-carbaguanine synthase, queE (gene)) is an enzyme with systematic name 6-carboxy-5,6,7,8-tetrahydropterin ammonia-lyase. This enzyme catalyses the following chemical reaction 6-carboxy-5,6,7,8-tetrahydropterin 7-carboxy-7-carbaguanine + NH3 The enzyme is a member of the superfamily of S-adenosyl-L-methionine-dependent radical enzymes.
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