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About: 6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Wikicat5-HT2CAntagonists, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatMolecularFormulasyago:Abstraction100002137yago:Adversary109773245yago:CausalAgent100007347yago:Communication100033020yago:Formula106816935yago:LivingThing100004258yago:Message106598915yago:MolecularFormula106817173yago:Object100002684yago:Organism100004475yago:Person100007846yago:PhysicalEntity100001930yago:YagoLegalActoryago:YagoLegalActorGeodrugyago:Statement106722453yago:Whole100003553yago:Wikicat5-HT2CAntagonists New Facet based on Instances of this Class

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.