The 25th Annual D.I.C.E. Awards is the 25th edition of the D.I.C.E. Awards ("Design Innovate Communicate Entertain"), an annual awards event that honors the best games in the video game industry during 2021. The awards were arranged by the Academy of Interactive Arts & Sciences (AIAS). The nominees were announced on January 13, 2022. The winners were announced in a ceremony at the Mandalay Bay Resort in Las Vegas on February 24, 2022. Ratchet & Clank: Rift Apart received the most nominations, and won the most awards, while It Takes Two won Game of the Year.