The 22nd Marine Regiment (22nd Marines) is an inactive United States Marine Corps infantry regiment. The regiment was commissioned in 1942 and was placed under the command of the 1st Provisional Marine Brigade, and the 6th Marine Division. It took part in fighting at the battles of Eniwetok, Guam, and Okinawa. The regiment also participated in the occupation of northern China following the war. 22d Marines was decommissioned in March 1946. The 22nd Marines was reactivated at Marine Corps Base Quantico, Virginia in 1947 and but was again decommissioned in October 1949.