The 2022 Spanish motorcycle Grand Prix (officially known as the Gran Premio Red Bull de España) was the sixth round of the 2022 Grand Prix motorcycle racing season and the first round of the 2022 MotoE World Cup. All races (except MotoE race 1, which was held on 30 April) were held at the Circuito de Jerez-Ángel Nieto in Jerez de la Frontera on 1 May 2022.