The 2022 Clemson Tigers baseball team were the varsity intercollegiate baseball team that represented Clemson University during the 2022 NCAA Division I baseball season. The Tigers competed in the Atlantic Coast Conference (ACC) and were led by seventh-year head coach Monte Lee. Clemson played its home games at Doug Kingsmore Stadium in Clemson, South Carolina. Infielder Max Wagner won ACC Player of the Year while leading the ACC in home runs, Slugging Percentage, and OPS. Wagner was also named a First Team All-American by Collegiate Baseball.