The 2021 Syracuse Orange women's soccer team represented Syracuse University during the 2021 NCAA Division I women's soccer season. The Orange were led by head coach Nicky Adams, in her third season. They played home games at SU Soccer Stadium. This is the team's 25th season playing organized women's college soccer, and their 8th playing in the Atlantic Coast Conference. The Orange finished the season 4–12–1, 0–10–0 in ACC play to finish in fourteenth place. They did not qualify for the ACC Tournament. They were not invited to the NCAA Tournament.