The 2021 Grand National (officially known as the Randox 2021 Grand National for sponsorship reasons) was the 173rd annual running of the Grand National horse race, held at Aintree Racecourse in Liverpool, England, on 10 April 2021. The event was once again sponsored by Randox Health, although the name on the race from this year onwards was shortened to simply "Randox". The total prize fund for the race was £750,000, down by £250,000 from the last meeting in 2019.