The 2021 CAF Women's Champions League WAFU Zone B Qualifiers is the enougural edition of the WAFU Zone B women's club football qualifier tournament organised by the WAFU for the women's clubs of association nations. This edition was held from 24 July to 5 August 2021 in Abidjan, Ivory Coast. The winners of the tournament qualified automatically for the 2021 CAF Women's Champions League final tournament, to be held in Egypt.