The 2021–22 VCU Rams men's basketball team represented Virginia Commonwealth University during the 2021–22 NCAA Division I men's basketball season. They are led by fifth-year head coach is Mike Rhoades and played their home games at the Siegel Center in Richmond, Virginia as a member of the Atlantic 10 Conference. They finished the season 22–10, 14–4 in A-10 play to finish in a tie for second place. As the No. 3 seed in the A-10 tournament, they lost in the quarterfinals to Richmond. They received an at-large bid to the National Invitation Tournament where they defeated Princeton in the first round before losing to Wake Forest.