The 2021–22 Stony Brook Seawolves women's basketball team represents Stony Brook University in the 2021–22 NCAA Division I women's basketball season. They play their home games at the Island Federal Credit Union Arena in Stony Brook, New York and are led by first-year head coach Ashley Langford, who took over the position after Caroline McCombs left to become the head coach for George Washington. They are members of the America East Conference.