The 2021–22 Ohio State Buckeyes men's basketball team represented Ohio State University in the 2021–22 NCAA Division I men's basketball season. Their head coach was Chris Holtmann, in his fifth season with the Buckeyes. The Buckeyes played their home games at Value City Arena in Columbus, Ohio as members of the Big Ten Conference. They finished the season 20–12, 12–8 in Big Ten play to finish a three-way tie for fifth place. As the No. 6 seed in the Big Ten tournament, they lost to Penn State in the quarterfinals. They received an at-large bid to the NCAA tournament as the No. 7 seed in the South region where they defeated in Loyola in the First Round before losing to Villanova in the Second Round.