The 2021–2022 NCAA conference realignment refers to extensive changes in NCAA conference membership, primarily at the Division I level, beginning in the 2021–22 academic year. Most of these changes have involved conferences in the Football Bowl Subdivision (FBS) of Division I. Of the 10 FBS conferences, seven will undergo changes in membership. Three conferences (Atlantic Coast Conference, Big Ten Conference, and Pac-12 Conference) formed an alliance of their own, but it did not prevent two Pac-12 members from announcing their move to the Big Ten.