The 2020–21 St. John's Red Storm men's basketball team represented St. John's University during the 2020–21 NCAA Division I men's basketball season. They are coached by Mike Anderson, in his second year at the school, and play their home games at Carnesecca Arena and Madison Square Garden as members of the Big East Conference. They finished the season 16-11, 10-9 in Big East Play to finish in 4th place. They lost in the quarterfinals of the Big East tournament to Seton Hall.