The 2020–21 Perth Scorchers Women's season was the sixth in the team's history. Coached by Shelley Nitschke and captained by Sophie Devine, the Scorchers played the entirety of WBBL|06 in a bio-secure Sydney hub due to the COVID-19 pandemic and, for the second year in a row, were eliminated in the semi-finals. In her first season with the Scorchers, Devine was named the league-wide Player of the Tournament, earning the same award that she won in WBBL|05 while playing for the Adelaide Strikers.