The 2020–21 Missouri State Bears basketball team represented Missouri State University during the 2020–21 NCAA Division I men's basketball season. The Bears, led by third-year head coach Dana Ford, played their home games at JQH Arena in Springfield, Missouri as members of the Missouri Valley Conference. In a season limited by the ongoing COVID-19 pandemic, they finished the season 17–7, 12–6 in MVC play to finish in third place. They defeated Valparaiso in the quarterfinals of the MVC tournament before losing to Drake in the semifinals.