The 2020–21 season was the club's 107th season in existence and the third consecutive season in the top flight of Greek football. In addition to the domestic league, Aris Thessaloniki participate in the Greek Football Cup and in the UEFA Europa League, from which they were eliminated in the second qualifying round by Ukrainian club Kolos Kovalivka. Aris changed managers in September, following the elimination in the Europa League, hiring Akis Mantzios