The 2019–20 Prairie View A&M Panthers basketball team represented Prairie View A&M University in the 2019–20 NCAA Division I men's basketball season. The Panthers, led by fourth-year head coach Byron Smith, played their home games at the William Nicks Building in Prairie View, Texas as members of the Southwestern Athletic Conference. They finished the season 19–13, 14–4 in SWAC play to be regular season SWAC champions. They defeated Alabama A&M in the quarterfinals of the SWAC tournament and were set to take on Jackson State in the semifinal before the tournament was cancelled amid the COVID-19 pandemic. With the SWAC Tournament cancelled, they were awarded the SWAC's automatic bid to the NCAA tournament. However, the NCAA Tournament was also cancelled.